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Synthesis of (+)-Bullatacin via the Highly Diastereoselective [3+2] Annulation Reaction of a Racemic Aldehyde and a Nonracemic Allylsilane

✍ Scribed by Tinsley, Jennifer M.; Mertz, Eric; Chong, Pek Y.; Rarig, Robert-André F.; Roush, William R.


Book ID
120251479
Publisher
American Chemical Society
Year
2005
Tongue
English
Weight
104 KB
Volume
7
Category
Article
ISSN
1523-7060

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✍ Chun-Yao Yang; Chiou-Dong Wang; Shu-Fan Tian; Rai-Shung Liu 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 214 KB 👁 1 views

## Abstract This work reports the novel gold‐catalyzed [3+2]/[2+2]‐annulation of allylsilane with 4‐methoxybut‐2‐yn‐1‐ols that yields highly strained bicyclo[3.2.0]heptene products efficiently and stereoselectively.