Diastereoselective alkylation of N-acylnorbornene sultams 2 afforded a variety of enantiomerically pure products 3a-3e. Reduction with LiAlH 4 (LAH) followed by ditosylation furnished chiral 1,4-ditosylates 5a-5e which underwent a cyclization reaction with primary amines to afford chiral 1,3-and 1,3
โฆ LIBER โฆ
Synthesis of bromoallenyl pyrrolidines via 1,4-addition to 1,3-enynes
โ Scribed by Jenny B. Werness; WeiPing Tang
- Book ID
- 107349264
- Publisher
- SP Science China Press
- Year
- 2011
- Tongue
- English
- Weight
- 415 KB
- Volume
- 54
- Category
- Article
- ISSN
- 1674-7291
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