The tetracycllc bridged-ring enones 1, 5 an& 3 have been prepared through acidcatalysed Intramolecular cycllsatlon of the dlazomethyl ketones 11, 16 and 22 respectively for entry Into the ring system of aphldlcolln( 4) and related dlterpenes --
Synthesis of bridged carbocyclic systems related to diterpenes involving intramolecular cyclisation of diazomethyl ketones
β Scribed by Basudeb Basu; Debabrata Mukherjee
- Publisher
- Elsevier Science
- Year
- 1984
- Tongue
- French
- Weight
- 145 KB
- Volume
- 25
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
β¦ Synopsis
The tricyclic dienediones 5,6 and L have been synthesised for entry into the ring systems of the tetracyclic diterpenes atisiFe;e (_1_), phyllocladene
(3) and hibaene ( 4) respectively.
Atisirene and isoatisirene are tetracyclic diterpenes isolated la from the mod of
π SIMILAR VOLUMES
R )-l-phenylethylamine-induced cyclization of ketoenoate 2 4 led to a 2:1 mixture of "all-cis" polycyclic adducts 2 5 and 2 6, structurally related to the taxane series. Ten years ago, we reported that chiral imines 3, derived from racemic 2-alkylcyclanones 1 and optically active 1-phenylethylamine