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Synthesis of bicyclo[6.2.2] bridgehead dienes

โœ Scribed by Yoshito Tobe; Yasuyoshi Ueda; Masaharu Matsumoto; Yasuo Sakai; Yoshinobu Odaira


Book ID
104220382
Publisher
Elsevier Science
Year
1982
Tongue
French
Weight
139 KB
Volume
23
Category
Article
ISSN
0040-4039

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Regiospecific synthesis of a bridgehead-
โœ Andrew S. Kende; Jiong Lan; Dorit Arad ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 87 KB

Three independent strategies are tested toward the synthesis of the protected 1-aminobicyclo[2.2.2]octene ketodiester 1. One of these three is found to be completely regioselective. It proceeds by Diels-Alder addition of dimethyl acetylenedicarboxylate to the silyl enol ether of 3-benzyloxycarbonyl-