Synthesis of Bicyclo[3.1.0]hexanes Functionalized at the Tip of the Cyclopropane Ring. Application to the Synthesis of Carbocyclic Nucleosides
β Scribed by Comin, Maria J.; Parrish, Damon A.; Deschamps, Jeffrey R.; Marquez, Victor E.
- Book ID
- 126092094
- Publisher
- American Chemical Society
- Year
- 2006
- Tongue
- English
- Weight
- 110 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1523-7060
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
The synthesis of a novel prostacyclin analog I has been achieved, incorporating as a key strategic feature a regio-controlled epoxide ring opening (as predicted by MM2 calculations) of a readily available prostaglandin synthon.
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
Treatment of nitroso Diels-Alder cycloadducts 1 with diazomethane in the presence of palladium acetate gives synthetically useful exo-6-oxa-7-azatricyclo[3.2.1.02,4]octane derivatives 7 in good to excellent yield. Using this methodology, a conformationally restricted 2',3'-methano carbocyclic nucleo