Synthesis of Biaryl Compounds by Vinylogous Michael Reactions

✍ Scribed by Jens Christoffers; Alexander Mann

• Publisher: John Wiley and Sons
• Year: 2000
• Tongue: English
• Weight: 288 KB
• Volume: 2000
• Category: Article
• ISSN: 1434-193X
• DOI: 10.1002/(sici)1099-0690(200005)2000:10<1977::aid-ejoc1977>3.0.co;2-z

✦ Synopsis

Acceptor-substituted cycloalkenones 1 undergo an iron(III)catalyzed vinylogous Michael reactiona sequence of enone-dienol tautomerism, [4+2]-cycloaddition, and retro-aldol reactionwith quinone derivatives 3. A variety of products is obtained ranging from meta-terphenyl precursors 5 to