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Synthesis of Benzoxazines, 3,4-Dihydroquinazolines and Quinazolinethiones

โœ Scribed by L. ElEfrit, M.; Hajjem, B.; Zantour, H.; Baccar, B.


Book ID
120011244
Publisher
Taylor and Francis Group
Year
1996
Tongue
English
Weight
264 KB
Volume
26
Category
Article
ISSN
0039-7911

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A novel method for solid-phase synthesis of dihydroquinazoline derivatives is presented. Polymer-bound 4-bromomethyl-3-nitrobenzoate and the corresponding amide are utilized as versatile precursors that undergo nucleophilic displacement with amines followed by reduction and cyclocondensation reactio