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Synthesis of benzofuran derivatives through the coupling of conjugated dienynes with Fischer carbene complexes

✍ Scribed by James W Herndon; Yi Zhang; Haixia Wang; Ke Wang


Publisher
Elsevier Science
Year
2000
Tongue
French
Weight
84 KB
Volume
41
Category
Article
ISSN
0040-4039

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The reaction of various carbene complexes with dienylacetylenes has been examined. The reaction has been used as the cornerstone for the preparation of the nor-neolignan natural product egonol in five steps from readily available components. In most examples of the carbene -alkyne coupling, the reac