## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract, please click on HTML or PDF.
Synthesis of Benz[c]benzothiopheno[2,3-e]azepines via Heck-Type Coupling and Pictet—Spengler Reaction.
✍ Scribed by Emilie David; Claudine Rangheard; Stephane Pellet-Rostaing; Marc Lemaire
- Publisher
- John Wiley and Sons
- Year
- 2006
- Weight
- 40 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0931-7597
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Synthesis of 3-Deaza-β-hydroxyhistidine Derivatives and Their Use for the Preparation of Substituted Pyrrolo[2,3-c]pyridine-5-carboxylates via the Pictet-Spengler Reaction. -The title compounds substituted in 4,5-and 5,7-positions are synthesized from histidine derivatives by Pictet-Spengler conden
## Abstract The Pictet‐Spengler reaction is performed as a one‐pot procedure by condensing thienylethylamine (I) with carbonyl compounds (II), followed by treatment of the in situ formed imines with acetic‐formic anhydride (III) to produce a formyliminium ion, which upon treatment with TFA cyclizes