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ChemInform Abstract: Synthesis of 3-Deaza-β-hydroxyhistidine Derivatives and Their Use for the Preparation of Substituted Pyrrolo[2,3-c]pyridine-5-carboxylates via the Pictet—Spengler Reaction.

✍ Scribed by J.-F. ROUSSEAU; R. H. DODD

Publisher: John Wiley and Sons
Year: 2010
Weight: 37 KB
Volume: 29
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.199836189

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✦ Synopsis

Synthesis of 3-Deaza-β-hydroxyhistidine Derivatives and Their Use for the Preparation of Substituted Pyrrolo[2,3-c]pyridine-5-carboxylates via the Pictet-Spengler Reaction.

-The title compounds substituted in 4,5-and 5,7-positions are synthesized from histidine derivatives by Pictet-Spengler condensation with aldehydes. The method may be extended to derivatives substituted at C-2 or C-3. -(ROUSSEAU,

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