## Abstract For Abstract see ChemInform Abstract in Full Text.
Synthesis of Azapolycyclic Systems via the Intramolecular [4 + 2] Cycloaddition Chemistry of 2-(Alkylthio)-5-amidofurans
β Scribed by Padwa, Albert; Ginn, John D.; Bur, Scott K.; Eidell, Cheryl K.; Lynch, Stephen M.
- Book ID
- 118749568
- Publisher
- American Chemical Society
- Year
- 2002
- Tongue
- English
- Weight
- 307 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0022-3263
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π SIMILAR VOLUMES
Cyclic 2-thiomethyl-5-amidofurans possessing tethered p-bonds were prepared by a dimethyl(methylthio) sulfonium tetrafluoroborate (DMTSF) induced cyclization of various amido dithioacetals. Upon heating, these systems undergo an intramolecular 4+2-cycloaddition reaction. The initially formed Diels-A
An efficient asymmetric synthesis in nine steps of natural (Γ)-pumiliotoxin C (1), a decahydroquinoline alkaloid found in the skin of Central American frog species, is presented. The enantiomerically pure starting material (S)-norvalinol (3), obtained from commercial (S)-norvaline, was cyclized in a