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Synthesis of aryl(γ-pyridyl)methanes and their conversion to substituted benzo[g]isoquinolines

✍ Scribed by N. F. Porstakov; V. I. Kuznetsov; V. F. Zakharov; V. P. Zvolinskii


Book ID
112351573
Publisher
Springer US
Year
1976
Tongue
English
Weight
396 KB
Volume
12
Category
Article
ISSN
0009-3122

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## Abstract Reaction of cyclopropanecarbaldehyde (I) with aryltitanium reagents, followed by tin‐catalyzed retro‐aldol—acetalization—lactonization sequence provides access towards γ‐aryllactones, e.g. (IV)/(V), with moderate to high diastereoselectivity.