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Synthesis of (.+-.)-Aporphine Utilizing Pictet—Spengler and Intramolecular Phenol ortho-Arylation Reactions.

✍ Scribed by Gregory D. Cuny


Publisher
John Wiley and Sons
Year
2004
Weight
21 KB
Volume
35
Category
Article
ISSN
0931-7597

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## Abstract magnified image New tetrahydroisoquinolines were synthesized by the Pictet‐Spengler reaction. Influence of a wide range of aryl and heteroaryl aldehydes, was investigated in the cyclization step with 3,4‐dimethoxyphenylethylamine **1**, L‐DOPA **2** and L‐3,4‐dimethoxyphenylalanine met