Synthesis of Apamin, a Neurotoxic Peptide from Bee Venom
✍ Scribed by Jurphaas VAN RIETSCHOTEN; Claude GRANIER; Hervé ROCHAT; Francois MIRANDA; Serge LISSITZKY
- Book ID
- 115114540
- Publisher
- John Wiley and Sons
- Year
- 1975
- Tongue
- English
- Weight
- 576 KB
- Volume
- 56
- Category
- Article
- ISSN
- 1432-1327
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📜 SIMILAR VOLUMES
**Potential value in the therapy of rheumatism and other inflammation processes** could attach to the MCD peptide from bee venom if it were available in larger quantities. The peptide consists of 22 amino acids and contains two disulfide bridges. Its first total synthesis has now been accomplished.
## Abstract The circular dichroism (CD) and ^1^H‐nmr properties of peptide 401, a bee venom component with 22 amino acid residues and two disulfide bridges, have been studied under a variety of conditions and compared with those of the structurally related octadecapeptide apamin. The major componen