## Abstract The circular dichroism (CD) and ^1^Hβnmr properties of peptide 401, a bee venom component with 22 amino acid residues and two disulfide bridges, have been studied under a variety of conditions and compared with those of the structurally related octadecapeptide apamin. The major componen
An Anti-Inflammatory Peptide from Bee Venom
β Scribed by BILLINGHAM, M. E. J.; MORLEY, J.; HANSON, JENNIFER M.; SHIPOLINI, R. A.; VERNON, C. A.
- Book ID
- 109687138
- Publisher
- Nature Publishing Group
- Year
- 1973
- Tongue
- English
- Weight
- 250 KB
- Volume
- 245
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/245163a0
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**Potential value in the therapy of rheumatism and other inflammation processes** could attach to the MCD peptide from bee venom if it were available in larger quantities. The peptide consists of 22 amino acids and contains two disulfide bridges. Its first total synthesis has now been accomplished.
## Abstract P2X3 purinoreceptors expressed in mammalian sensory neurons play a key role in several processes, including pain perception. From the venom of the Central Asian spider __Geolycosa__ sp., we have isolated a novel peptide, named purotoxinβ1 (PT1), which is to our knowledge the first natur