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An Anti-Inflammatory Peptide from Bee Venom

✍ Scribed by BILLINGHAM, M. E. J.; MORLEY, J.; HANSON, JENNIFER M.; SHIPOLINI, R. A.; VERNON, C. A.


Book ID
109687138
Publisher
Nature Publishing Group
Year
1973
Tongue
English
Weight
250 KB
Volume
245
Category
Article
ISSN
0028-0836

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**Potential value in the therapy of rheumatism and other inflammation processes** could attach to the MCD peptide from bee venom if it were available in larger quantities. The peptide consists of 22 amino acids and contains two disulfide bridges. Its first total synthesis has now been accomplished.

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## Abstract P2X3 purinoreceptors expressed in mammalian sensory neurons play a key role in several processes, including pain perception. From the venom of the Central Asian spider __Geolycosa__ sp., we have isolated a novel peptide, named purotoxin‐1 (PT1), which is to our knowledge the first natur