Synthesis and estrogen receptor binding
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Chung K. Rhee; Kun Chae; Louis A. Levy; Kenneth S. Korach
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Article
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1995
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Elsevier Science
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English
β 207 KB
Synthesis of fluorinated DES and hexestrol derivatives starting from 4-methoxybenzaldehyde is described. The structures of the fluorinated compounds were characterized by NMR. The fluorinated DES derivatives bind to the mouse uterine cytosol estrogen receptor with high affinity.