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Synthesis of analogues of the biphenomycin antibiotics

✍ Scribed by Allan G. Brown; Peter D. Edwards

Publisher
Elsevier Science
Year
1990
Tongue
French
Weight
246 KB
Volume
31
Category
Article
ISSN
0040-4039

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AbstractÐABC analogues of the antitumour antibiotic streptonigrin, that contain the key metal chelation site and redox-active quinone unit that are essential for biological activity, were prepared via palladium catalysed cross-coupling of 2-iodo-8-nitroquinoline or 2-iodo-6methoxy-5-nitroquinoline w