N-Glycosylation is a widespread posttranslational modification of eukaryotic proteins. N-Glycans are functional constituents of glycoproteins and serve to control the intra-and intercellular distribution and three-dimensional structure of glycoproteins and also protect them against degradation. Furt
Synthesis of an α-(2,3)-Sialylated, Complex-Type Undecasaccharide
✍ Scribed by Joachim Seifert; Matthias Lergenmüller; Yukishige Ito
- Publisher
- John Wiley and Sons
- Year
- 2000
- Tongue
- English
- Weight
- 131 KB
- Volume
- 39
- Category
- Article
- ISSN
- 0044-8249
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## Background: Biosynthesis of sialyl lewis(x) (sle(x)) requires a sialyltransferase for alpha-2,3-sialylation and a fucosyltransferase for alpha-1,3-fucosylation. to date, five human alpha-1,3-fucosyltransferase (fuc-t) genes and five human alpha-2,3-sialyltransferase (st) genes have been cloned.
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