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Synthesis of an Unsaturated β-Alanine Derivative

✍ Scribed by G. N. Khimich; M. Yu. Slabospitskaya; V. A. Korzhikov; T. B. Tennikova


Book ID
106518945
Publisher
SP MAIK Nauka/Interperiodica
Year
2005
Tongue
English
Weight
44 KB
Volume
78
Category
Article
ISSN
1070-4272

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Heterocyclic [3-substituted alanine derivatives such as [3-(pyrazol-l-yl) and 13-(l,2,4-triazol-l-yl)-alanine are synthesized in high yields by a Michael addition of heterocyclic nucleophiles to N,N-bis(tert-butyloxycarbonyl)dehydroalanine methyl ester, using mild reaction conditions and simple work