Synthesis of an azido spermidine equivalent
โ Scribed by Alexander L. Weis; Tamas Bakos; Ivan Alferiev; Xuehai Zhang; Bin Shao; William A. Kinney
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- French
- Weight
- 118 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0040-4039
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โฆ Synopsis
The synthesis and conversion era new spermidine equivalent (2) to squalamine is reported. It is prepared in a practical manner, is stable to sodium borohydride reduction, is converted to spermidine under mild conditions, and is not prone to internal cyclization reactions.
๐ SIMILAR VOLUMES
a short synthesis of a spermidine conjugating agent is presented. Spermidine, 1, is implicated in diverse physiological processes that share as a common thread a close relationship to cell proliferation and growth; in particular, it associates with polyanions such as DNA and RNAs . Spermidine deriva
An asymmetric synthesis of (~)-(4R)-dihydroisomyricoidine (28). a 13-membered amino lactam of type A. was performed by a diastereoselective Mic,hae/ addition between the spermidine derivative 3 and the commercially available optically active ethyl carboxylate 4, and the cyclization of the resulting