Asymmetric 1,4-additions to 5-alkoxy-2(5
β
Ben L. Feringa; Ben De Lange
π
Article
π
1988
π
Elsevier Science
π
French
β 765 KB
The synthesis of enantiomerically pure 5-menthyloxy-2(5B)-furanones is described as well as the diastereoselective 1,4-addition of thiols to these butenolides to yield new homochiral CQ-synthons. Kinetic resolution of 5-methoxy-2(5H)-furanone, with an enautiameric excess of 139, wae achieved by cinc