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Synthesis of an Azide-Bearing N -Mustard Analogue of S -Adenosyl- l -methionine

โœ Scribed by Mai, Van; Comstock, Lindsay R.


Book ID
126013628
Publisher
American Chemical Society
Year
2011
Tongue
English
Weight
273 KB
Volume
76
Category
Article
ISSN
0022-3263

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Facile Hydrogen-Deuterium Exchange at th
โœ Olafur Th. Magnusson; Perry A. Frey ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 161 KB

S-3ะˆ,4ะˆ-anhydroadenosyl-L-methionine is an analogue of the S-adenosyl-L-methionine coenzyme. Here we report on a rapid solvent exchange of the methylene protons at the 5ะˆ-position of this analogue. The rate of H/D exchange was measured by nuclear magnetic resonance spectroscopy under buffered condit