Facile Hydrogen-Deuterium Exchange at th
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Olafur Th. Magnusson; Perry A. Frey
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Article
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2002
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Elsevier Science
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English
⚖ 161 KB
S-3Ј,4Ј-anhydroadenosyl-L-methionine is an analogue of the S-adenosyl-L-methionine coenzyme. Here we report on a rapid solvent exchange of the methylene protons at the 5Ј-position of this analogue. The rate of H/D exchange was measured by nuclear magnetic resonance spectroscopy under buffered condit