Synthesis of an Alanyl Adenosine Analog
β Scribed by Botta, Oliver; Strazewski, Peter
- Book ID
- 111641915
- Publisher
- Taylor and Francis Group
- Year
- 1999
- Tongue
- English
- Weight
- 119 KB
- Volume
- 18
- Category
- Article
- ISSN
- 0732-8311
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Selective borohydride reduction of adenosine dialdehyde (1) gave the known adenosine 2'monoaldehyde (2). Reaction of I with N,N'-diphenylethylenediamine, followed by reduction and deblocking gave adenosine 3'-monoaldehyde ($), a new compound. Unlike 2, compound $ inhibited S-AdoHcy hydrolase and sho
## Abstract The syntheses of the acyclic MDP analogs 27β37 is described, the carbohydrate moiety of muramic acid being replaced by acyclic amino alcohol structures. Their preparation was accomplished by hydrolytic cleavage of the cyclic, disubstituted 3βmorpholinones 2β5 and protection of the free