Synthesis of an Advanced Maoecrystal V Core Structure

✍ Scribed by Dr. Lin Dong; Dr. Lujiang Deng; Dr. Yee Hwee Lim; Dr. Gulice Y. C. Leung; Prof. Dr. David Y.-K. Chen

• Publisher: John Wiley and Sons
• Year: 2011
• Tongue: English
• Weight: 224 KB
• Volume: 17
• Category: Article
• ISSN: 0947-6539
• DOI: 10.1002/chem.201100232

✦ Synopsis

Traditional Chinese medicine is an active and fruitful research field in both a chemical and a biological context. Bioactive components originating from herbal extracts not only present themselves as leads for the development of novel chemotherapeutics, but also serve as a vehicle for advancing synthetic organic chemistry to new heights. [1] During an extraction effort in the mid 1990s from the leaves of Isodon eriocalyx, collected from the Jiangchuan prefecture of the Yunnan province, a number of new diterpenoids were reported. [2] Maoecrystal V (1, Scheme 1