Structure-Based Design and Synthesis of
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Corinne Baumgartner; Christian Eberle; François Diederich; Susan Lauw; Felix Roh
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Article
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2007
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John Wiley and Sons
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German
⚖ 583 KB
## Abstract In this paper, we describe the structure‐based design, synthesis, and biological evaluation of cytosine derivatives and analogues that inhibit IspF, an enzyme in the non‐mevalonate pathway of isoprenoid biosynthesis. This pathway is responsible for the biosynthesis of the C~5~ precursor