Pyrimethamine, an antimalarial drug, was found to be able to inhibit both enzymes (DHFR-TS and PTR1) of the leishmanial folate pathway, although this effect in vivo appears only in relatively high concentrations. To reach the parasites inside macrophage cells, where they are sheltered, targeted drug
Synthesis of aminoanthraquinone derivatives and their in vitro evaluation as potential anti-cancer drugs
โ Scribed by Jehoshua Katzhendler; Keria-Fiorella Gean; Gidon Bar-Ad; Zeev Tashma; Raphael Ben-Shoshan; Israel Ringel; Uriel Bachrach; Avner Ramu
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 821 KB
- Volume
- 24
- Category
- Article
- ISSN
- 0223-5234
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