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Synthesis of aminoacyl thiaolidones as potential antitumour agents

✍ Scribed by Ana Cristina Lima Leite; Luciene Maria F. Santos; Fábio Fernandes Barbosa; Marcos V. de Oliveira Cardoso; Diogo Rodrigo M. Moreira; Ivone Antonia de Souza

Book ID
116313626
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
205 KB
Volume
60
Category
Article
ISSN
0753-3322

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✍ Ahmed Kamal; P Ramulu; O Srinivas; G Ramesh 📂 Article 📅 2003 🏛 Elsevier Science 🌐 English ⚖ 125 KB

The facile synthesis of C-8 methanesulphonate substituted pyrrolobenzodiazepines is described. These have been prepared by linking the methanesulphonate at C-8 position with alkanol spacer and their in vitro cytotoxicity have been described.