Enantioselective addition of diethylzinc
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Sudhir N Joshi; Sanjay V Malhotra
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Article
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2003
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Elsevier Science
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English
β 121 KB
A (+)-3-carene derived aminoalcohol was successfully used as a chiral ligand in the catalytic enantioselective diethylzinc addition to various aldehydes. Very high enantiomeric excess (up 98% in 1-(2-methoxyphenyl)-1-propanol) was obtained. A plausible mechanism has been suggested for the observed e