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Synthesis of amides by aminolysis of esters using sodium hydride in dimethyl sulfoxide

โœ Scribed by Baldev Singh

Publisher
Elsevier Science
Year
1971
Tongue
French
Weight
77 KB
Volume
12
Category
Article
ISSN
0040-4039

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โœฆ Synopsis

N-Substituted amides have been prepared by aminolysiB of esters using the magnesium halide,' eodiumae3 and lithium3 salts of primary amines. Sodium methoxide4 and bifunctional catalysts (such as 2-pyridone)5 have aleo been employed in the aminolyeis of esters by primary amine8 but yield8 are not uniformly high and no general method seems available for such aminolysis.

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