Reverse Brook rearrangement of 2-alkynyl
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Kazuhiko Sakaguchi; Masato Fujita; Hiroyuki Suzuki; Masato Higashino; Yasufumi O
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Article
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2000
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Elsevier Science
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French
β 166 KB
A new method for the synthesis of optically active a-hydroxyalkynylsilane 3 is described. The key step of the conversion to 3 was the use of the reverse Brook rearrangement of the 2-alkynyl silyl ether 2.