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Synthesis of (.alpha.-hydroxyalkyl)trialkylsilanes via a reverse Brook rearrangement

✍ Scribed by Linderman, Russell J.; Ghannam, Ameen


Book ID
126795763
Publisher
American Chemical Society
Year
1988
Tongue
English
Weight
378 KB
Volume
53
Category
Article
ISSN
0022-3263

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A new method for the synthesis of optically active a-hydroxyalkynylsilane 3 is described. The key step of the conversion to 3 was the use of the reverse Brook rearrangement of the 2-alkynyl silyl ether 2.

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