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Synthesis of alkyl/aryl [11C-carbonyl] aromatic ketones using [11C]carbon monoxide

✍ Scribed by J. Barletta; M. Björkman; M. Ögren; B. Långström


Book ID
112132805
Publisher
John Wiley and Sons
Year
2001
Tongue
French
Weight
95 KB
Volume
44
Category
Article
ISSN
0022-2135

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Synthesis of [11C-carbonyl]hydroxyureas
✍ Julien Barletta; Farhad Karimi; Bengt Långström 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 French ⚖ 107 KB

11 C]Hydroxyurea has been successfully labelled using [ 11 C]carbon monoxide at low concentration. The decay-corrected radiochemical yield was 38 AE 3%, and the trapping efficiency of [ 11 C]carbon monoxide in the order of 90 AE 5%. This synthesis was performed by a rhodium-mediated carbonylation