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Palladium-mediated synthesis of [carbonyl-11C]amides and hydrazides using [11C]carbon monoxide

โœ Scribed by Karimi, Farhad; L??ngstr??m, Bengt

Book ID
121227067
Publisher
Royal Society of Chemistry
Year
2002
Weight
97 KB
Volume
18
Category
Article
ISSN
1472-7781

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Synthesis of [11C-carbonyl]hydroxyureas
Synthesis of [11C-carbonyl]hydroxyureas by a rhodium-mediated carbonylation reaction using [11C]carbon monoxide
โœ Julien Barletta; Farhad Karimi; Bengt Lรฅngstrรถm ๐Ÿ“‚ Article ๐Ÿ“… 2006 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 107 KB

11 C]Hydroxyurea has been successfully labelled using [ 11 C]carbon monoxide at low concentration. The decay-corrected radiochemical yield was 38 AE 3%, and the trapping efficiency of [ 11 C]carbon monoxide in the order of 90 AE 5%. This synthesis was performed by a rhodium-mediated carbonylation