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Synthesis of aliphatic isocyanates via a two-phase Hofmann reaction

โœ Scribed by Anita O. Sy; Joseph W. Raksis


Book ID
107858193
Publisher
Elsevier Science
Year
1980
Tongue
French
Weight
185 KB
Volume
21
Category
Article
ISSN
0040-4039

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The solid phase synthesis of oxazolidinones via a novel cylisation/cleavage reaction is described. Resin bound carbamates 2, which were obtained by reaction of Wang-resin with commereiaily available isoeyanates 1, were alkylated with glycidyltosylate to the corresponding epoxides 3. Nueleophilic ope