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Synthesis of Albendazole Metabolite: Characterization and HPLC Determination

✍ Scribed by Mahler, Graciela; Davyt, Danilo; Gordon, Sandra; Incerti, Marcelo; Núñez, Ivana; Pezaroglo, Horacio; Scarone, Laura; Serra, Gloria; Silvera, Mauricio; Manta, Eduardo

Book ID
120008913
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
228 KB
Volume
85
Category
Article
ISSN
0021-9584

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## ABSTRACT The development and validation of an LC‐MS/MS method for the simultaneous determination of albendazole metabolites (albendazole sulfoxide and albendazole sulfone) in human plasma are described. Samples of 200 μL were extracted with ether–dichloromethane–chloroform (60:30:10, v/v/v). The