Synthesis of acylphosphonyl analogues of phosphatidyl-myo-inositol as inhibitors of phosphatidylinositol-specific phospholipase C
โ Scribed by Maria A. Alisi; Mario Brufani; Luigi Filocamo; Luciano Cellai; M.Adelaide Iannelli; Maria C. Cesta; Sperandina Lappa
- Publisher
- Elsevier Science
- Year
- 1994
- Tongue
- English
- Weight
- 354 KB
- Volume
- 265
- Category
- Article
- ISSN
- 0008-6215
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A fluorescent water-soluble substrate for phosphatidylinositol-specific phospholipase C was synthesized. The diacylglycerol moiety of the natural substrate, phosphatidylinositol, was replaced by the fluorescent moiety, 2-naphthol, resulting in the synthetic substrate, racemic 2-naphthyl myo-inositol
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