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Synthesis of acetyl-substituted heterocyclic ketene aminals and their deacetylation reaction

โœ Scribed by Wang, He-Ting ;Wang, Xiao-Jun ;Huang, Zhi-Tang


Publisher
Wiley (John Wiley & Sons)
Year
1990
Tongue
English
Weight
416 KB
Volume
123
Category
Article
ISSN
0009-2940

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Regioselective Acylation of Heterocyclic Ketene Aminals with Acetyl Chloride. -Acylation of ketene aminals (I) affords exclusively the N-acylated products (IV), while in the presence of triethylamine and Hg(CN)2 the C-acylated products (III) predominate together with (IV) as minor products. The (E)