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Synthesis of a trans-hydrindane nuclear analog of 11-desoxy-dihydro-prostaglandin E1

✍ Scribed by Peter B. Anzeveno


Book ID
119048759
Publisher
Elsevier Science
Year
1978
Tongue
English
Weight
228 KB
Volume
16
Category
Article
ISSN
0090-6980

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πŸ“œ SIMILAR VOLUMES


Stereoselective synthesis of [11 Ξ²-3H]pr
✍ G. L. Bundy; J. A. Easter; L. S. Banitt; Y. Philopoulos; A. J. Wickrema Sinha; R πŸ“‚ Article πŸ“… 1993 πŸ› John Wiley and Sons 🌐 French βš– 533 KB

## Abstract This report describes an efficient stereoselective synthesis of [11β‐^3^H]prostaglandin E~1~ ([11β‐^3^H]PGE~1~). The key multiply protected 11‐keto intermediate was prepared in only three steps from PGE~1~. Reduction of the ketone function at C‐11 with sodium borodeuteride and sodium bo