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Synthesis of 11-dehydro-13,14-dihydro-PGE1 [prostaglandin E1] and -PGD2 [prostaglandin D2]

✍ Scribed by Hayashi, Masaki; Tanouchi, Tadao


Book ID
126230503
Publisher
American Chemical Society
Year
1973
Tongue
English
Weight
186 KB
Volume
38
Category
Article
ISSN
0022-3263

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## Abstract Chemical and enzymatic tools were employed to synthesize [1,1‐^18^O~2~]‐prostaglandin (PG) E1, [1,1‐^18^O~2~]‐13,14‐dihydro‐15‐keto‐PGE~1~ and [5,6‐^3^H~2~]‐13,14‐dihydro‐15‐keto‐PGE~1~ starting from the corresponding unlabelled compounds adn [5,6‐^3^H~2~]‐PGE~1~, respectively. Reaction