Synthesis of a Thio-Analogue of Lewis X by Regioselective Opening of Cyclic Sulfamidates. -The synthesis of the title analogue (I) contains linking of galactose and allosamine, protected by a p-methoxyphenyl group at O-6 (higher yield), transformation into cyclic sulfamidate, and its regioselective
Synthesis of a Thio-Analogue of Lewis X by Regioselective Opening of Cyclic Sulfamidates
✍ Scribed by Aguilera, Begoña; Fernández-Mayoralas, Alfonso
- Book ID
- 125483286
- Publisher
- American Chemical Society
- Year
- 1998
- Tongue
- English
- Weight
- 88 KB
- Volume
- 63
- Category
- Article
- ISSN
- 0022-3263
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Efficient and general synthetic methods for novel chiral peraza-macrocycles have been developed. Sequential reactions of the known cyclic sulfamidate 4 derived from N-benzyl-L-serine methyl ester with pmethoxybenzylamine provided a symmetric triamine 3, which served as a building block for the const