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Synthesis of a series of polar, orthogonally protected, α,α-disubstituted amino acids

✍ Scribed by T.Scott Yokum; Matthew G. Bursavich; Sarina A. Piha-Paul; David A. Hall; Mark L. McLaughlin

Publisher: Elsevier Science
Year: 1997
Tongue: French
Weight: 264 KB
Volume: 38
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(97)00822-8

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✦ Synopsis

The synthesis of four novel, "cationic", a,u-disubstituted amino acids is described. The new amino acids use an orthogonal protection scheme making them suitable for incorporation via solid-phase peptide synthesis.

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