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Synthesis of a porphyrin-labelled carboranyl phosphate diester: a potential new drug for boron neutron capture therapy of cancer

โœ Scribed by Maderna, Andreas; Huertas, Ramon; Hawthorne, M. Frederick; Luguya, Raymond; Vicente, M. Gra??a H.


Book ID
115439288
Publisher
Royal Society of Chemistry
Year
2002
Tongue
English
Weight
106 KB
Volume
16
Category
Article
ISSN
1359-7345

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Synthesis of rac-1-(9-o-carboranyl)nonyl
โœ Peter Lemmen; Birgit Werner ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Elsevier Science ๐ŸŒ English โš– 469 KB

Boron-containing analogues of ether lipids are proposed as boron carriers in the boron neutron capture therapy (BNCT). The syn-the~ of rac-I-(9-o-Carboranyl)nonyl-2-methyl-glycero-3-phosphocholine (B-Et-I l-OMe) as a in'st representative is described. The carborane is introduced into the readily ass