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Synthesis of a Novel Series of 6-Chloro-1,4,2-benzodithiazine 1,1-Dioxide Derivatives with Potential Biological Activity.

✍ Scribed by Z. Brzozowski; F. Saczewski


Publisher
John Wiley and Sons
Year
2006
Weight
28 KB
Volume
37
Category
Article
ISSN
0931-7597

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✍ Elżbieta Pomarnacka; Anita Kornicka; Anna Kuchnio; Maike Heinrichs; Renate Grüne 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 472 KB 👁 2 views

## Abstract A new series of 16 6‐chloro‐1,1‐dioxo‐7‐{4‐[(4‐R^1^‐phenyl)imino]‐4__H__‐3,1‐benzoxazin‐2‐yl}‐3‐(substituted amino)‐1,4,2‐benzodithiazines **7–22** was prepared in order to evaluate the cytotoxic activity against six human cancer cell lines. The structures of the new compounds were conf