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ChemInform Abstract: Synthesis, Cytotoxicity Testing, and Structure—Activity Relationships of Novel 6-Chloro-7-(4-phenylimino-4H-3,1-benzoxazin-2-yl)-3- (substituted)-1,4,2-benzodithiazine 1,1-Dioxides.

✍ Scribed by Elzbieta Pomarnacka; Anita Kornicka; Anna Kuchnio; Maike Heinrichs; Renate Gruenert; Maria Gdaniec; Patrick J. Bednarski

Publisher
John Wiley and Sons
Year
2011
Weight
30 KB
Volume
42
Category
Article
ISSN
0931-7597

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Synthesis, Cytotoxicity Testing, and Str
Synthesis, Cytotoxicity Testing, and Structure–Activity Relationships of Novel 6-Chloro-7-(4-phenylimino-4H-3,1-benzoxazin-2-yl)-3-(substituted)-1,4,2-benzodithiazine 1,1-dioxides
✍ Elżbieta Pomarnacka; Anita Kornicka; Anna Kuchnio; Maike Heinrichs; Renate Grüne 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 472 KB 👁 2 views

## Abstract A new series of 16 6‐chloro‐1,1‐dioxo‐7‐{4‐[(4‐R^1^‐phenyl)imino]‐4__H__‐3,1‐benzoxazin‐2‐yl}‐3‐(substituted amino)‐1,4,2‐benzodithiazines **7–22** was prepared in order to evaluate the cytotoxic activity against six human cancer cell lines. The structures of the new compounds were conf