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Synthesis, Structural Characterization and in vitro Antitumor Activity of 4-Dimethylaminopyridinium (6-Chloro-1,1-dioxo-1,4,2-benzodithiazin-3-yl)methanides.

โœ Scribed by Zdzislaw Brzozowski; Franciszek Saczewski; Maria Gdaniec


Publisher
John Wiley and Sons
Year
2004
Weight
148 KB
Volume
35
Category
Article
ISSN
0931-7597

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## Abstract A new series of 16 6โ€chloroโ€1,1โ€dioxoโ€7โ€{4โ€[(4โ€R^1^โ€phenyl)imino]โ€4__H__โ€3,1โ€benzoxazinโ€2โ€yl}โ€3โ€(substituted amino)โ€1,4,2โ€benzodithiazines **7โ€“22** was prepared in order to evaluate the cytotoxic activity against six human cancer cell lines. The structures of the new compounds were conf