Syntheses of some sialic acid-containing nucleotide sugars are reported. The reaction of methyl [(2-hydroxy)ethyl 5-acetamido-4,7,8,9-tetra-O-acetyl-3,5-dideoxy-D-glycero-alpha-D-galacto -2-nonulopyranosid]onate (4) with various fully protected hydrogen phosphonates of nucleosides (5a-c) in the pres
✦ LIBER ✦
Synthesis of a novel dioxan sialic acid analog
✍ Scribed by Françoise M. Perron-Sierra; Mike Burbridge; Christophe Péan; Gordon C. Tucker; Patrick Casara
- Book ID
- 118501478
- Publisher
- Elsevier Science
- Year
- 2004
- Tongue
- French
- Weight
- 283 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0040-4039
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## Abstract Poly(1,__N__^6^‐etheno‐2‐aza‐adenylic acid) [poly(2‐aza‐εA)] was synthesized from 1,__N__^6^‐etheno‐2‐aza‐adenosine 5′‐diphosphate (2‐aza‐εADP) and __Escherichia coli__ polynucleotide phosphorylase. The values __K__~__m__~ = 1.02 m__M__, __V__ = 1.06 μmol hr^−1^ enzyme unit^−1^ were fou