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Synthesis of a New Series of 4-Aryl-1,4-Dihydropyridines with Calcium Channel Blocking and Vasodilatory Activity

✍ Scribed by Ranju Bansal, Priyanka Jain, Carmen Calle, Rosalia Carron, Karen Pemberton, Alan L. Harvey

Book ID
113015065
Publisher
Springer-Verlag
Year
2011
Tongue
English
Weight
417 KB
Volume
21
Category
Article
ISSN
1054-2523

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Synthesis and Calcium Channel Blocking A
Synthesis and Calcium Channel Blocking Activity of 4-Indolyl-1,4-dihydropyridines
✍ Rodolfo Lavilla; Teresa Gotsens; M.Carmen Santano; Joan Bosch; Antoni Camins; No πŸ“‚ Article πŸ“… 1997 πŸ› Elsevier Science 🌐 English βš– 229 KB

A series of indolyldihydropyridines has been designed, synthesized, and evaluated in order to show the effect of the indole moiety and the role of the methyl groups at the 2 and 6 positions of the dihydropyridine ring in the calcium channel blocking activity. The results seem to show that these grou