Synthesis of a new pyrimidine nucleoside analog related to uridine
β Scribed by T. Ling Chwang; Charles Heidelberger
- Publisher
- Elsevier Science
- Year
- 1974
- Tongue
- French
- Weight
- 161 KB
- Volume
- 15
- Category
- Article
- ISSN
- 0040-4039
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A new route to the synthesis of pyrazole and pyrimidine C-nucleosides, which involves as the key step a metal promoted reaction of ~-D-ribofuranosyl ketoesters with alkyl cyanoformates is described. 2,3,5-Tri-O-benzoyl-~-D-ribofuranosyl cyanide I reacts with ct-bromoesters, in the presence of zinc d
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