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Synthesis of a new class of electron rich chiral cyclophanes with large cavities

โœ Scribed by Perumal Rajakumar; Muthialu Srisailas


Book ID
104205369
Publisher
Elsevier Science
Year
2003
Tongue
French
Weight
120 KB
Volume
59
Category
Article
ISSN
0040-4020

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A new method for the synthesis of maleate(and phthalate )-bridged cyclophanes is described. For example, cyclophanes 4 (or 5) were obtained in 37-55 % yields by treating maleic (or phthalic) anhydride with various benzene dimethanols and reacting the resulting bis-carboxylate salts with various a, o