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Synthesis of a Model DEF-Ring Core of Hexacyclinic Acid.

✍ Scribed by Paul A. Clarke; Matthew Grist; Mark Ebden; Claire Wilson

Publisher: John Wiley and Sons
Year: 2003
Weight: 139 KB
Volume: 34
Category: Article
ISSN: 0931-7597
DOI: 10.1002/chin.200342226

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## Abstract For Abstract see ChemInform Abstract in Full Text.

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## on the occasion of his 60th birthday Lomaiviticins A (1) and B (2, Figure 1) were isolated in 2001 from the fermentation broth of a species of the actinomycete genus Micromonospora. [1] Both natural products were shown to be highly active DNA-damaging agents. The more abundant compound, lomaivit